教授保罗trayhurn FRSE

教授研究员

paul.trayhurn@buckingham.ac.uk

Professor Paul Trayhurn在克洛尔实验室
英国澳门皇家赌场
亨特街
白金汉
MK18 1EG,英国
电话(办公室):01280八十二万○二百四十二分之八十二万○二百四十
传真:01280 820135

度:BSC(读取),哲学博士,DSC(氧磷)。保罗trayhurn在2011年8月正式加入大学的研究策略(兼职)的院长,已用克洛尔实验室自2009年起名誉教授有关。

His previous appointments include: NATO European Research Fellowship in Strasbourg, France; Scientific/Senior Staff, MRC Dunn Nutrition Laboratory, Cambridge; Professor and Heritage Scholar in Nutrition & Metabolism, University of Alberta, Canada; Head of the Division of Biomedical 科学, Rowett 研究 Institute, Aberdeen (Honorary Professor, University of Aberdeen); Professor of Nutritional Biology, University of Oslo, Norway. He was appointed to the Chair of Nutritional Biology at the University of Liverpool in 2001 and was Director of the Obesity Biology Unit; he is now an Emeritus Professor at Liverpool and an Honorary Professor in the University of Sydney Medical School.

Paul Trayhurn is a Fellow of the Royal Society of Edinburgh. He won the international André Mayer Prize in 1983 (given for outstanding work in the field of obesity for an investigator aged under 40), the Friedrich Wasserman Award in 2008 from the European Association for the Study of Obesity (for lifetime contributions to obesity research), and the Kaufmann Memorial Lecture Award in 2009 from the International Society for Fat Research. He is Chairman of both the Scientific and Awards Committees of the International Association for the 研究 of Obesity; he has also been a member of the BBSRC Agri-Food Committee and the MRC Population & Systems 医学 Board, and is a former Editor-in-Chief of the British Journal of Nutrition. His current external activities include membership of the Research Board (Biological 科学s) of the Royal Society and of the 研究 Committee of Diabetes UK, and he is a Trustee of the Nutrition Society. He is the author of 300 peer-reviewed publications on energy metabolism, OBesity and adipose tissue function; his published work has received >13,500 citations.

研究

  • 能量平衡和肥胖 - 产热
  • 脂肪组织生物学,特别是:(ⅰ)脂肪组织作为分泌和内分泌器官,(ⅱ)在调节脂肪组织功能缺氧作用,(ⅲ)脂肪组织既作为维生素d目标和存储站点

同行评审出版物(选择)的

trayhurn P,thurlby PL,詹姆斯WPT(1977)。在肥胖前期热缺陷 的ob / OB 老鼠。 性质 266:60-62 DOI:10.1038 / 266060a0  

布鲁克斯SL,罗斯韦尔新泽西州,股票MJ,古德博迪AE,trayhurn P(1980)。在表现出饮食诱导产热大鼠褐色脂肪组织增加线粒体质子电导通路。  性质 286:274-276 DOI:10.1038 / 286274a0

trayhurn P,琼斯时,mcguckin毫米,古德博迪AE(1982)。填饲对能量平衡和褐色脂肪产热在肥胖的影响(的ob / OB) 老鼠。 性质 295:323-325 DOI:10.1038 / 295323a0

trayhurn P,道格拉斯JB,mcguckin毫米(1982)。在小鼠哺乳期间棕色脂肪组织产热是“抑制”。 性质 298:59-60 DOI:10.1038 / 289699a0

géloën一个,trayhurn P(1990)。解偶联蛋白的棕色脂肪组织中的胰岛素水平的调控。 上午生理学杂志 258:R418-r424

trayhurn P,邓肯JS,雷纳DV(1995年)。急性感冒引起的抑制 OB 在小鼠的白色脂肪组织(肥胖)的基因表达:调解交感神经系统。 生物化学杂志 311: 729-733

比蒂JH,木材时,纽曼时许,布雷姆纳我,周仰杰KHA,AE的Michalska,邓肯JS,trayhurn P(1998)。 hyperleptinaemia和金属硫蛋白肥胖(-i和-II)缺失小鼠。 国家科学院院刊美国 95: 358-363 dx.doi.org/10.1073/pnas.95.1.358

trayhurn P,木材(2004年)。脂肪因子:炎症和白色脂肪组织的多效性作用。 BRĴNUTR 92:347-355 dx.doi.org/10.1079/bjn20041213

冰C,宝Y,詹金斯Ĵ,打磨器P,manieri米,cinti S,Tisdale的MJ,trayhurn P(2004)。锌 - 2 - 糖蛋白,脂质动员因子,在脂肪细胞中表达,并与癌症恶病质小鼠中上调。 国家科学院院刊美国 101:二五○○年至2505年 http://dx.doi.org/10.1016/j.febslet.2004.11.042

王斌,木材,trayhurn P(2007)。通过在人脂肪细胞缺氧的表达和炎症相关的脂肪因子的分泌失调。 pflügers档案馆EUR生理学杂志 455:479-492 dx.doi.org/10.1007/s00424-007-0301-8

奥哈拉一个,LIM F-L,mazzatti DJ,trayhurn P(2009)。微阵列分析识别基质金属蛋白酶(MMP)作为关键基因,其表达由巨噬细胞条件培养基中的人脂肪细胞中被上调。 pflügers档案馆EUR生理学杂志 458:一一○三年至1114年 DOI:10.1007 / s00424-009-0693-8

trayhurn P(2013年)。缺氧和脂肪组织功能和肥胖功能障碍。 生理学转 93:1-21 DOI:10.1152 / physrev.00017.2012

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